Bacterial Resistance to Antibiotics: From Molecules to Man (Original PDF from Publisher)

The Fight Against Superbugs: Unlocking New Antibiotics in a Post-Antibiotic Era

In the realm of healthcare, the advent of antibiotics heralded a paradigm shift in treating infectious diseases, drastically reducing mortality rates and extending lifespans. However, this medical triumph faces a formidable challenge today: the alarming surge in antibiotic-resistant superbugs.

The Centers for Disease Control and Prevention (CDC) estimates that over two million such infections plague the United States each year, claiming approximately 23,000 lives. Despite the dire public health implications, the pipeline of new antibiotics in development or undergoing clinical trials remains scarce.

To avert a return to the pre-antibiotic era, where infectious diseases were often deadly and virtually untreatable, novel and groundbreaking approaches are necessary to combat the growing resistance of pathogenic bacteria.

The Crossroads of Antibiotic Resistance and Molecular Science

“Bacterial Resistance to Antibiotics – From Molecules to Man” delves into the intricate tapestry of antibiotic resistance, exploring the current state and future trajectory of research into next-generation antibiotics that will redefine clinical practice.

An esteemed consortium of international experts unravels an array of critical topics, including:

• The enigmatic mechanisms of glycopeptide antibiotic resistance
• Innovative anti-tuberculosis agents to combat the deadly scourge
• Anti-virulence therapies that target bacterial virulence factors
• Tetracyclines: Uncovering new facets of an established antibiotic class
• The molecular and structural determinants that dictate resistance

A Multifaceted Approach to Overcoming Resistance

This comprehensive compendium emphasizes a multidisciplinary approach to optimize novel antibiotics for maximum potency while minimizing toxicity and ensuring appropriate degradability. It illuminates the crucial aspects that can alleviate the pressing medical crisis of antibiotic resistance.

Public Health and the Global Burden

The book underscores the intertwined nature of antibiotic resistance, global public health, and longevity. It offers a thorough overview of the genetic and molecular mechanisms underlying resistance, contextualizing this scientific understanding within the larger framework of contemporary public health concerns.

A Resource for Practitioners and Scholars Alike

“Bacterial Resistance to Antibiotics – From Molecules to Man” is an invaluable resource for practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields. It provides up-to-date information, comprehensive references, author insights, and a wealth of captivating visuals, graphs, and charts.

As we navigate the uncharted waters of the post-antibiotic era, this book serves as a beacon of hope, guiding us towards a future where infectious diseases no longer hold the upper hand.