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Nunn’s Applied Respiratory Physiology: A Comprehensive Guide to Respiratory Function
Functional Anatomy and Mechanics of Respiration
Nunn’s Applied Respiratory Physiology provides an in-depth understanding of the structural and functional components of the respiratory system. It delves into the anatomy of the airways, lungs, and thorax, describing their role in facilitating gas exchange. The book explores the mechanics of breathing, explaining the forces involved in inspiration and expiration, and the impact of lung compliance and resistance on respiratory function.
Control of Breathing and Ventilation-Perfusion Matching
The book discusses the complex mechanisms that regulate breathing, including the role of the central and peripheral chemoreceptors, the vagus nerve, and the respiratory centers in the brainstem. It examines the factors that influence ventilation-perfusion matching, ensuring the efficient delivery of oxygen to the blood and removal of carbon dioxide.
Diffusion, Gas Transport, and Pulmonary Circulation
Nunn’s Applied Respiratory Physiology explores the principles of gas diffusion, describing the movement of gases across the alveolar-capillary membrane. It covers the transport of oxygen and carbon dioxide in the blood, including the role of hemoglobin and the Bohr effect. The book also examines the pulmonary circulation, explaining the unique adaptations that optimize gas exchange within the lungs.
Physiological Responses to Altered Conditions
The book delves into the physiological responses to various stressors and altered conditions. It examines the respiratory effects of pregnancy, exercise, sleep, altitude, pressure, drowning, smoking, anaesthesia, hypocapnia, hypercarbia, hypoxia, hyperoxia, and anaemia. These sections provide valuable insights into the respiratory adaptations that occur in response to these conditions.
Clinical Disorders of the Respiratory System
Nunn’s Applied Respiratory Physiology explores specific clinical disorders that affect the respiratory system. It covers ventilatory failure, airways disease, pulmonary vascular disease, parenchymal lung disease, and acute lung injury. The book discusses the pathophysiology of these disorders and the physiological basis of current therapies, including artificial ventilation, extrapulmonary gas exchange, and lung transplantation.
Surgical Interventions in Pulmonary Disease
The book includes a dedicated chapter on pulmonary surgery, providing a comprehensive overview of surgical interventions for pulmonary diseases. It covers bronchoscopy, lung resection, and other surgical techniques, explaining the physiological implications and outcomes of these procedures.
Updated Literature and Expert Insights
The Seventh Edition of Nunn’s Applied Respiratory Physiology includes almost 500 new references to the latest literature, ensuring that it remains an up-to-date and authoritative resource. The book also features contributions from leading experts in the field, providing valuable perspectives on respiratory physiology and clinical practice.
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